Perlstein Lab

Leave no mutation behind

PLab is the first Public Benefit Corporation accelerating precision drug discovery for 5,000+ rare genetic diseases.

  • 1 in 12 people has an orphan disease. 95% of orphan diseases have no treatment.

  • Each disease is caused
    by a spectrum of genetic mutations.

  • Perlstein Lab studies each mutation
    in model organisms to produce precision medicine.


From primary screen to mouse validation, Part 3

Last month I traveled to Tucson for my third consecutive Ara Parseghian Medical Research Foundation meeting for Niemann-Pick Type C/NPC. In 2014 at my first APMRF meeting, which was hosted in South Bend at Notre Dame University, I was a newcomer to the NPC community but eager to introduce PLab’s platform to the academic brain […]