1 in 12 people has an orphan disease. 95% of orphan diseases have no treatment.
Each disease is caused
by a spectrum of genetic mutations.
Perlstein Lab studies each mutation
in model organisms to produce precision medicine.
Leave no mutation behind
PLab is the first Public Benefit Corporation accelerating precision drug discovery for 5,000+ rare genetic diseases.
Here I’ll sum up a recent paper in Developmental Cell by E. Thomas Danielson and Morten E. Moeller. The paper, entitled “A Drosophila Genome-Wide Screen Identifies Regulators of Steroid Hormone Production and Developmental Timing,” utilized the Vienna Drosophila RNAi Center’s RNAi collection. This is a set of thousands of fly strains, where each enables the expression of […]