1 in 12 people has an orphan disease. 95% of orphan diseases have no treatment.
Each disease is caused
by a spectrum of genetic mutations.
Perlstein Lab studies each mutation
in model organisms to produce precision medicine.
Leave no mutation behind
Perlstein Lab PBC is a San Francisco-based biotech startup and public benefit corporation focused on precision orphan drug discovery.
As the cell biology lead at Perlstein Lab, I spend a lot of time thinking about ways to better understand the mechanism of action of the hits from our primary screens. There are many experiments one can do to try to narrow down what pathway their compound is affecting such as cell biology experiments in […]